High-Purity FOXO4 Peptide for Sale | Shanghai Apeptide

Welcome to Shanghai Apeptide Co., Ltd., your definitive source for premium foxo4 peptide for sale. If you are a researcher or a supply company in the USA seeking a reliable, wholesale partner, you have found it. As an authentic, licensed manufacturer headquartered in Shanghai, China, we bridge the gap between advanced peptide synthesis and your laboratory’s precise requirements.

Our foundation of quality is built at our primary physical location: No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. From this advanced facility, we oversee all peptide synthesis operations, ensuring that every shipment of foxo4 peptide meets our unwavering 99% purity standard. We invite you to explore our comprehensive range and discover the Apeptide difference.  foxo4 peptide for sale

Understanding the Senolytic Peptide

FOXO4-DRI (D-Retro-Inverso) is a synthetic peptide designed to selectively target and eliminate senescent cells—often called “zombie cells”—that accumulate with aging and contribute to various age-related diseases . It is a 21-amino acid peptide that disrupts the interaction between the FOXO4 and p53 proteins within the nucleus of senescent cells .

Scientists study FOXO4-DRI for its key roles in:

• Senolytic Activity: It is one of the most well-known senolytic compounds, specifically designed to induce apoptosis (programmed cell death) in senescent cells while sparing healthy, dividing cells .

• FOXO4-p53 Disruption: It competitively binds to p53, blocking the FOXO4-p53 interaction that normally keeps senescent cells alive despite their damaged state .

• Cellular Aging Research: It serves as a valuable tool for studying the fundamental mechanisms of cellular senescence and its contribution to organismal aging .    foxo4 peptide for sale

• Age-Related Disease Models: Researchers use FOXO4-DRI to investigate potential therapeutic approaches for conditions where senescent cell accumulation plays a role, including vascular aging, pulmonary fibrosis, and fibrotic disorders .

It is essential to state clearly: FOXO4 peptide is supplied strictly for research and laboratory use only. It is not for human consumption or medical application.

The Science Behind FOXO4-DRI: A Research Overview

FOXO4-DRI represents a groundbreaking approach in senescence research, offering a targeted method to study the elimination of harmful senescent cells.

How Does FOXO4-DRI Work?

FOXO4-DRI’s unique mechanism centers on its ability to competitively disrupt a specific protein-protein interaction that keeps senescent cells alive. Its primary research-relevant actions include:     foxo4 peptide for sale

1. Disruption of FOXO4-p53 Binding: In senescent cells, FOXO4 binds to p53 within the nucleus, preventing p53 from triggering apoptosis. FOXO4-DRI mimics the FOXO4 binding domain and competitively displaces FOXO4 from p53 .

2. Nuclear Exclusion of p53: Once displaced, p53 is released and translocates from the nucleus to the cytoplasm .

3. Activation of Apoptosis: In the cytoplasm, p53 activates pro-apoptotic proteins like BAX and cleaved caspase-3, initiating the cell’s natural self-destruct sequence selectively in senescent cells .

Key Research Context and Resources

• Senolytic Discovery: FOXO4-DRI was first described in a landmark 2017 study demonstrating its ability to restore tissue homeostasis in aged and chemotherapy-treated mice . Researchers rely on authoritative databases like  search for FOXO4-DRI for emerging chemical information.

• Extensive Scientific Literature: A search on will yield numerous peer-reviewed papers covering its effects on vascular aging , pulmonary fibrosis , keloid scarring , and chondrocyte senescence . This body of work underscores the critical need for high-purity, reliable peptides for reproducible research. foxo4 peptide for sale

Why Choose Shanghai Apeptide for Your Research Needs?

When your experiments depend on accuracy and consistency, your choice of supplier is paramount. Here is why leading labs choose us for foxo4 peptide supply.

1. Uncompromising Quality and 99% Purity

We are the manufacturer, not a distributor. Our synthesis facility in the Pudong District of Shanghai is dedicated to producing peptides of the highest caliber. Every batch of our foxo4 peptide is synthesized and purified to achieve 99% purity. This guarantees your experimental data reflects the true properties of the compound, free from confounding impurities.

2. Direct Manufacturer-Direct Pricing

By sourcing directly from Shanghai Apeptide Co., Ltd., you eliminate supply chain markups. This means you acquire premium, licensed products at genuinely competitive wholesale prices. This makes us the ideal partner for both small, specialized labs and large-scale US-based supply companies.

3. Specialized Expertise in Peptide Chemistry

Our core mission is the research, development, and manufacture of biochemicals, with a deep focus on peptides, fluorescent dyes, and amino acids. This specialization ensures we understand your need for consistency, proper documentation, and technical support. Trust that your order of FOXO4 for sale is handled with expert care.

Committed to Global Research Standards

Our manufacturing philosophy aligns with the expectations of the international scientific community. For researchers seeking deeper insights into FOXO4-DRI and its applications, resources like the National Institutes of Health (NIH) offer extensive, peer-reviewed data via PubMed. Broader discussions on research methodologies and emerging senolytic compounds can also be found on professional platforms like Medium. These resources all underscore the same principle: valid science requires high-quality, reliable materials.

For a broader view of our quality standards, explore our detailed product page on . You can also review the specifications for another advanced research compound in our catalog.

Frequently Asked Questions About FOXO4 Peptide

1: Is this FOXO4 peptide for human consumption?
No. Absolutely not. Shanghai Apeptide Co., Ltd. supplies foxo4 peptide for sale strictly for research and laboratory purposes only. It is not approved or intended for human consumption, medical use, or veterinary application.

2: What purity level do you guarantee for FOXO4-DRI?
We specialize in Premium High Quality 99% Purity Peptides. Our FOXO4-DRI is rigorously synthesized and tested to meet this high standard consistently, ensuring reliability for your sensitive research protocols.

3: Can I order FOXO4-DRI in bulk for my supply company?
Yes, we are a dedicated wholesale supplier. We welcome inquiries and orders of all sizes. Visit our shop to see our product range and contact our team for customized bulk pricing.

4: How should FOXO4 peptide be stored for research?
For optimal stability, FOXO4-DRI (typically supplied as a lyophilized powder) should be stored at -20°C, protected from light and moisture. Please refer to the Certificate of Analysis (CoA) included with your order for specific storage guidelines.

5: Are you a legitimate, licensed manufacturer based in China?
Yes. Shanghai Apeptide Co., Ltd. is a professional, authentic manufacturer. Our headquarters and peptide synthesis operations are located at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. We are fully dedicated to the compliant research, development, and marketing of diverse biochemical products.  foxo4 peptide for sale

Ready to Source Premium FOXO4 for Your Research?

Do not compromise on the quality of your critical research materials. As a premier peptide manufacturer in China, Shanghai Apeptide is your direct, reliable source for the high-purity raw materials you need to advance discovery in senescence and aging research.

Whether you need a small quantity for a specific study or a consistent wholesale supply for your business, our team is ready to support you. Experience the confidence of working with a trusted, licensed supplier.  foxo4 peptide for sale