Sermorelin Acetate Peptide for Sale – Direct from Shanghai Manufacturer
Sermorelin represents a cornerstone in growth hormone research, serving as a potent and selective analog of growth hormone-releasing hormone (GHRH). This 29-amino acid peptide was specifically designed to stimulate endogenous growth hormone (GH) secretion in a physiological manner, making it an invaluable research tool for scientists investigating the GH axis, endocrine function, and metabolic regulation . If you are searching for “sermorelin peptide for sale” for your laboratory investigations, you need a manufacturing partner who understands the complexity of this GHRH analog and can deliver the purity your studies demand. That partner is Apeptide (Shanghai) Co., Ltd.
We are a legitimate, licensed manufacturer operating from our headquarters at No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai, China. Our facility is dedicated to the research, development, and production of high-purity peptide raw materials, catalog peptides, fluorescent dyes, and amino acids. When you purchase sermorelin acetate peptide from shanghaiapeptides.com, you are buying directly from the source—not a middleman or reseller.
Understanding Sermorelin: The GHRH Analog
Sermorelin is a synthetic 29-amino acid peptide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH) . It is the shortest fragment of GHRH that retains full biological activity, making it a highly selective and effective tool for GH research. sermorelin peptide for sale
Key Characteristics
| Parameter | Specification |
|---|---|
| Sequence | H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂ |
| Molecular Formula | C₁₄₉H₂₄₆N₄₄O₄₂S |
| Molecular Weight | Approximately 3,357.9 g/mol |
| CAS Number | 86168-78-7 |
| Salt Form | Acetate salt (enhanced stability and solubility) |
| Form | Lyophilized powder |
| Purity | ≥99% (verified by HPLC) |
| Storage | -20°C, protected from light and moisture |
Mechanism of Action: The GHRH Pathway
| Pathway | Mechanism | Research Implications |
|---|---|---|
| GHRH Receptor Activation | Binds to and activates GHRH receptors on pituitary somatotrophs | Growth hormone regulation, receptor pharmacology |
| GH Stimulation | Stimulates endogenous growth hormone release in a dose-dependent manner | Somatotroph function, GH pulsatility |
| IGF-1 Induction | Increases insulin-like growth factor-1 (IGF-1) production | Growth factor signaling, metabolic regulation |
| Physiological Pulsatility | Mimics natural pulsatile GH secretion pattern | Endocrine physiology, feedback mechanisms |
| Synergistic Effects | Works synergistically with GHRPs (e.g., ipamorelin) | Combinatorial signaling, endocrinology |
Why Sermorelin Matters in Research
Sermorelin is one of the most well-characterized GHRH analogs in scientific literature. Its selective action on the GHRH receptor and its ability to stimulate physiological GH release have made it a benchmark compound in endocrinology research. sermorelin peptide for sale
Key Research Applications
| Research Area | Key Findings | Research Context |
|---|---|---|
| Growth Hormone Research | Potent GH stimulator; EC₅₀ in low nanomolar range; induces physiological GH pulsatility | Endocrinology, pituitary function |
| GHRH Receptor Pharmacology | Selective GHRH receptor agonist; used to characterize receptor binding and signaling | Receptor pharmacology, drug development |
| Aging Research | Counteracts age-related GH decline (somatopause) | Gerontology, age-related metabolic changes |
| Metabolic Research | Influences lipid metabolism, body composition, and insulin sensitivity | Obesity, metabolic regulation |
| Pituitary Function | Used to assess pituitary somatotroph reserve | Diagnostic research, pituitary disorders |
| Combination Studies | Synergistic effects with GHRPs (GHRP-2, GHRP-6, ipamorelin) | Combinatorial endocrinology |
Key Research Insights
| Finding | Significance |
|---|---|
| Full Biological Activity | The 29-amino acid fragment retains full GH-releasing activity of native GHRH (44 amino acids) |
| Selective Action | Does not stimulate other pituitary hormones (prolactin, ACTH, TSH) |
| Physiological Pulsatility | Stimulates GH in a pulsatile pattern that mimics natural secretion |
| Short Half-Life | Rapidly metabolized (~5-10 minutes); useful for pulse studies |
The Critical Importance of Quality for Sermorelin Research
When you purchase sermorelin peptide for sale, quality parameters are non-negotiable. Sermorelin is a 29-amino acid peptide requiring precise synthesis to ensure correct sequence, C-terminal amidation, and full biological activity. sermorelin peptide for sale
The Apeptide Quality Standard
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99% Purity Guarantee: Verified by High-Performance Liquid Chromatography (HPLC)
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Mass Spectrometry: Molecular weight confirmation (3,357.9 g/mol expected)
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Amino Acid Analysis: Sequence verification of all 29 amino acids
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C-Terminal Amidation Confirmation: Essential for receptor binding and activity
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Peptide Content Determination: Accurate net peptide weight (≥80% typical)
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Counterion Analysis: Acetate content specified
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Water Content: ≤8.0% by Karl Fischer
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Endotoxin Testing: <0.05 EU/mg available for cell culture applications
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Batch-Specific COAs: Full traceability with Certificates of Analysis
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Stability Testing: Ensuring integrity from our lab to yours
Why Purity Matters for Sermorelin Research
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Receptor Binding Studies: EC₅₀ values in nanomolar range require precise dosing
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In Vivo Studies: Dosing consistency critical for GH and IGF-1 measurements
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Cell Culture Applications: Impurities affect somatotroph viability
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Mechanistic Studies: Pathway analysis demands documented purity
The Manufacturer Advantage: Why Source Sermorelin from Apeptide
When you search for “sermorelin peptide for sale,” you encounter many options. Here is why direct sourcing from our Shanghai facility is the superior choice. sermorelin peptide for sale
Complete Transparency
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Physical Location: We operate from No. B Room 326, Jinhai Road 2588, Pudong District, Shanghai. You can verify our credentials.
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Manufacturing Expertise: Decades of combined experience in peptide synthesis and biochemical production.
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No Middlemen: You pay manufacturer-direct pricing, not reseller markups.
Technical Expertise
Our team understands the specific requirements for sermorelin research:
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Importance of C-terminal amidation for receptor binding
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Proper handling to maintain peptide stability
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Appropriate reconstitution for various assay systems
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Storage conditions to prevent degradation
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Documentation requirements for research compliance
Quality You Can Trust
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Rigorous Testing: Every batch undergoes HPLC and MS analysis
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Documentation: Full COAs provided for complete traceability
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Consistency: Reliable quality batch after batch
Seamless Supply to the USA Market
Sourcing sermorelin acetate peptide from China should be straightforward. We have optimized our logistics specifically for American researchers and wholesale partners.
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Fast Shipping: 5-7 business days to US addresses
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Cold-Chain Packaging: Temperature-controlled transit at -20°C for sensitive peptides
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Desiccant Protection: Double-sealed packaging to prevent moisture absorption
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Wholesale Programs: Dedicated support for small and large supply companies
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Customs Expertise: Smooth clearance with complete documentation
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Tracking Integration: Real-time visibility from Shanghai to your lab
Research Applications: Where Sermorelin Excels
Understanding the diverse applications of sermorelin helps researchers appreciate why quality matters. sermorelin peptide for sale
Endocrinology Research
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GH pulsatility and regulation studies
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Pituitary somatotroph function
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GHRH receptor binding and signaling
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Feedback mechanisms (IGF-1, somatostatin)
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Pituitary reserve assessment
Metabolic Research
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GH/IGF-1 axis and energy homeostasis
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Lipid metabolism and body composition
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Insulin sensitivity and glucose regulation
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Adipose tissue biology
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Metabolic syndrome models
Aging Research
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Somatopause models
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Age-related GH decline
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Frailty and sarcopenia studies
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Bone metabolism and osteoporosis
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Muscle wasting investigations
Receptor Pharmacology
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GHRH receptor binding studies
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Structure-activity relationship investigations
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Biased agonism and signaling selectivity
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Comparative studies with GHRP compounds
Combination Research
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Synergistic effects with GHRPs (ipamorelin, GHRP-2, GHRP-6)
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Pulsatile GH secretion studies
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Combinatorial endocrine signaling
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Drug interaction investigations
Frequently Asked Questions
: What exactly is sermorelin acetate peptide for sale at Apeptide?
A: Sermorelin is a synthetic 29-amino acid peptide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH). It selectively activates GHRH receptors on pituitary somatotrophs, stimulating endogenous growth hormone secretion. It is supplied strictly for laboratory investigation and in vitro research only, not for human consumption. sermorelin peptide for sale
: What purity levels do you guarantee for sermorelin?
A: We guarantee 99% purity, verified by HPLC testing with Certificates of Analysis available for every batch. Each COA provides detailed purity analysis, mass spectrometry confirmation (3,357.9 g/mol expected), and batch-specific data.
: What is the CAS number for sermorelin?
A: The CAS number for sermorelin is 86168-78-7 .
: What is the molecular weight of sermorelin?
A: The molecular weight is approximately 3,357.9 g/mol .
: How does sermorelin differ from full-length GHRH (44 amino acids)?
A: Sermorelin is the 29-amino acid N-terminal fragment of GHRH, which retains full biological activity. The shorter sequence is more stable and easier to synthesize while maintaining complete GH-releasing potency . sermorelin peptide for sale
: What is the primary mechanism of sermorelin?
A: Sermorelin binds to GHRH receptors on pituitary somatotrophs, activating the cAMP signaling pathway and stimulating the synthesis and release of growth hormone in a physiological pulsatile pattern .
: Is your sermorelin for human consumption?
A: Absolutely not. Our sermorelin is strictly for research and laboratory use only. It is not for human consumption, clinical application, or any use involving humans or animals. All products are labeled “FOR RESEARCH USE ONLY.”
: How should I store sermorelin upon receipt?
A: Sermorelin should be stored at -20°C (freezer) immediately upon receipt, protected from light and moisture. Lyophilized powder is stable when stored properly. Avoid repeated freeze-thaw cycles.
: What solvent should I use for reconstitution?
A: For most research applications, sterile water, PBS (pH 7.4), or cell culture medium is appropriate. Sermorelin is soluble in aqueous buffers. Contact our technical team for application-specific recommendations.
: Do you ship to all 50 US states?
A: Yes. We ship to research institutions, laboratories, and wholesale partners throughout the United States.
: Can you accommodate bulk orders for wholesale distribution?
A: Absolutely. We offer competitive wholesale pricing for qualified partners. Contact our team through shanghaiapeptides.com with your volume requirements.
: What documentation do you provide for research compliance?
A: Every order includes batch-specific Certificates of Analysis (COAs) with HPLC and MS data. We also provide commercial invoices, packing lists, and customs documentation as needed. sermorelin peptide for sale
Quality Control: The Apeptide Standard
Your research deserves nothing less than the highest purity materials. Our quality control protocols exceed industry standards. sermorelin peptide for sale
Analytical Methods
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HPLC Analysis: Every batch tested for purity (typically 99%+)
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Mass Spectrometry: ESI-MS or MALDI-TOF for molecular weight confirmation (3,357.9 Da expected)
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Amino Acid Analysis: Sequence verification of all 29 amino acids
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C-Terminal Amidation Confirmation: Essential for biological activity
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Peptide Content Determination: Accurate net peptide weight (≥80% typical)
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Counterion Analysis: Acetate content specified
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Water Content: ≤8.0% by Karl Fischer
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Endotoxin Testing: <0.05 EU/mg available for cell culture applications
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Stability Studies: Ensuring integrity under various conditions
Batch Documentation
Each shipment includes:
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Certificate of Analysis with actual test results
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HPLC chromatogram (available upon request)
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Mass spectrometry data
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Batch number for traceability
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Expiration date and storage recommendations
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Reconstitution guidelines
Beyond Sermorelin: A Complete Research Partner
Apeptide (Shanghai) Co., Ltd. is more than just a supplier of sermorelin peptide for sale. We are a full-service biochemical manufacturer committed to advancing research worldwide.
Our Capabilities
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Custom Synthesis: Develop proprietary peptides for your specific research needs
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Catalog Peptides: Hundreds of sequences available for immediate shipment
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Growth Hormone Research Library: Including GHRH analogs, GHRPs, and related peptides
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Fluorescent Dyes: High-purity labeling agents for imaging and detection
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Amino Acids: Building blocks for synthesis and research
Quality Certifications & Compliance
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Licensed manufacturer with physical facility in Pudong District, Shanghai
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Rigorous quality control protocols
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Transparent documentation and traceability
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Experienced technical support team
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Strict adherence to research-use-only compliance
The Science Behind Sermorelin: The Biologically Active GHRH Fragment
Sermorelin was developed following the discovery that the GH-releasing activity of GHRH resides in its N-terminal region . The native human GHRH is a 44-amino acid peptide, but research demonstrated that the first 29 amino acids retain full biological activity .
The peptide’s structure includes: sermorelin peptide for sale
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N-terminal tyrosine: Critical for receptor binding
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C-terminal amidation: Essential for biological activity
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Specific arginine residues: Important for receptor interaction
Key characteristics that make sermorelin a valuable research tool:
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Selectivity: Does not stimulate other pituitary hormones (prolactin, ACTH, TSH)
-
Physiological Action: Stimulates GH in a pulsatile pattern mimicking natural secretion
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Well-Characterized: Extensively studied in both basic and clinical research
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Short Half-Life: Rapid clearance (~5-10 minutes) enables pulse studies
Sermorelin’s selective action on the GHRH receptor and its ability to stimulate physiological GH release have made it a benchmark compound for studying: sermorelin peptide for sale
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Growth hormone regulation and pulsatility
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Pituitary somatotroph function
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GHRH receptor pharmacology
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Age-related GH decline (somatopause)
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Synergistic effects with GHRPs
The search for premium “sermorelin peptide for sale” ends at Apeptide (Shanghai) Co., Ltd. As a dedicated manufacturer of peptides and biochemicals, we combine scientific expertise with manufacturing integrity to deliver the purest research materials available. Whether you need sermorelin for growth hormone research, metabolic studies, aging investigations, or specialized endocrine applications, we are your trusted manufacturing partner. sermorelin peptide for sale







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